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3′,4′-dihydroxyflavonol ameliorates endoplasmic reticulum stress-induced apoptosis and endothelial dysfunction in mice
Endoplasmic reticulum (ER) stress has been implicated in the development of hypertension 3 through the induction of endothelial impairment. As 3′,4′-dihydroxyflavonol (DiOHF) 4 reduces vascular injury caused by ischaemia/reperfusion or diabetes, and flavonols have been demonstrated to attenuate ER s...
Autores principales: | Lau, Yeh Siang, Mustafa, Mohd Rais, Choy, Ker Woon, Chan, Stanley M. H., Potocnik, Simon, Herbert, Terence P., Woodman, Owen L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789000/ https://www.ncbi.nlm.nih.gov/pubmed/29379034 http://dx.doi.org/10.1038/s41598-018-19584-8 |
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