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Effects of Toremifene, a Selective Estrogen Receptor Modulator, on Spontaneous and Stimulated GH Secretion, IGF-I, and IGF-Binding Proteins in Healthy Elderly Subjects

CONTEXT: Estrogens amplify spontaneous and stimulated growth hormone (GH) secretion, whereas they diminish GH-dependent insulin-like growth factor (IGF)-I in a dose-dependent manner. Selective estrogen receptor modulators (SERMs), including tamoxifen and toremifene, are widely adjunctively used in b...

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Detalles Bibliográficos
Autores principales: Roelfsema, Ferdinand, Yang, Rebecca J., Takahashi, Paul Y., Erickson, Dana, Bowers, Cyril Y., Veldhuis, Johannes D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789038/
https://www.ncbi.nlm.nih.gov/pubmed/29383334
http://dx.doi.org/10.1210/js.2017-00457