Cargando…

The antidepressant fluoxetine acts on energy balance and leptin sensitivity via BDNF

Leptin and Brain Derived Neurotrophic Factor (BDNF) pathways are critical players in body weight homeostasis. Noninvasive treatments like environmental stimulation are able to increase response to leptin and induce BDNF expression in the brain. Emerging evidences point to the antidepressant selectiv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Scabia, Gaia, Barone, Ilaria, Mainardi, Marco, Ceccarini, Giovanni, Scali, Manuela, Buzzigoli, Emma, Dattilo, Alessia, Vitti, Paolo, Gastaldelli, Amalia, Santini, Ferruccio, Pizzorusso, Tommaso, Maffei, Lamberto, Maffei, Margherita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789051/ https://www.ncbi.nlm.nih.gov/pubmed/29379096 http://dx.doi.org/10.1038/s41598-018-19886-x

Ejemplares similares

Environment, Leptin Sensitivity, and Hypothalamic Plasticity
por: Mainardi, Marco, et al.
Publicado: (2013)

Haptoglobin Is Required to Prevent Oxidative Stress and Muscle Atrophy
por: Bertaggia, Enrico, et al.
Publicado: (2014)

Fluoxetine treatment promotes functional recovery in a rat model of cervical spinal cord injury
por: Scali, Manuela, et al.
Publicado: (2013)

Congenital Generalized Lipoatrophy (Berardinelli-Seip Syndrome) Type 1: Description of Novel AGPAT2 Homozygous Variants Showing the Highly Heterogeneous Presentation of the Disease
por: Ceccarini, Giovanni, et al.
Publicado: (2020)

Circulating Levels of MiRNAs From 320 Family in Subjects With Lipodystrophy: Disclosing Novel Signatures of the Disease
por: Dattilo, Alessia, et al.
Publicado: (2022)

Reduced Responsiveness to Long-Term Monocular Deprivation of Parvalbumin Neurons Assessed by c-Fos Staining in Rat Visual Cortex
por: Mainardi, Marco, et al.
Publicado: (2009)

Haptoglobin deficiency determines changes in adipocyte size and adipogenesis
por: Gamucci, Olimpia, et al.
Publicado: (2012)

Obesity-Associated Hepatosteatosis and Impairment of Glucose Homeostasis Are Attenuated by Haptoglobin Deficiency
por: Lisi, Simonetta, et al.
Publicado: (2011)

Editorial: Leptin Resistance in Metabolic Disorders: Possible Mechanisms and Treatments
por: Hosoi, Toru, et al.
Publicado: (2017)

Editorial: Metabolic Mediators and Synapses: Linking Body Periphery to Neural Plasticity
por: Maffei, Margherita, et al.
Publicado: (2019)

How physical and motor training affect cognitive performance: lessons from an inflammatory molecule
por: Maffei, Margherita, et al.
Publicado: (2022)

Vascular Dysfunction in a Mouse Model of Rett Syndrome and Effects of Curcumin Treatment
por: Panighini, Anna, et al.
Publicado: (2013)

Ciliary Neurotrophic Factor Acts on Distinctive Hypothalamic Arcuate Neurons and Promotes Leptin Entry Into and Action on the Mouse Hypothalamus
por: Venema, Wiebe, et al.
Publicado: (2020)

Environmental Enrichment Effects on Development of Retinal Ganglion Cell Dendritic Stratification Require Retinal BDNF
por: Landi, Silvia, et al.
Publicado: (2007)

The obesity and inflammatory marker haptoglobin attracts monocytes via interaction with chemokine (C-C motif) receptor 2 (CCR2)
por: Maffei, Margherita, et al.
Publicado: (2009)

Artificial Neural Networks in the Outcome Prediction of Adjustable Gastric Banding in Obese Women
por: Piaggi, Paolo, et al.
Publicado: (2010)

Environmental Enrichment Modulates Cortico-Cortical Interactions in the Mouse
por: Di Garbo, Angelo, et al.
Publicado: (2011)

Atypical Progeroid Syndrome and Partial Lipodystrophy Due to LMNA Gene p.R349W Mutation
por: Magno, Silvia, et al.
Publicado: (2020)

Adjunctive treatment of brexpiprazole with fluoxetine shows a rapid antidepressant effect in social defeat stress model: Role of BDNF-TrkB signaling
por: Ma, Min, et al.
Publicado: (2016)

Environmental enrichment strengthens corticocortical interactions and reduces amyloid-β oligomers in aged mice
por: Mainardi, Marco, et al.
Publicado: (2014)

Intranasal delivery of BDNF rescues memory deficits in AD11 mice and reduces brain microgliosis
por: Braschi, Chiara, et al.
Publicado: (2020)

Evaluation of the antidepressant activity of Moringa oleifera alone and in combination with fluoxetine
por: Kaur, Ginpreet, et al.
Publicado: (2015)

Fibroblast growth factor 2 is necessary for the antidepressant effects of fluoxetine
por: Simard, Stephanie, et al.
Publicado: (2018)

Potential Role of the Antidepressants Fluoxetine and Fluvoxamine in the Treatment of COVID-19
por: Mahdi, Mohamed, et al.
Publicado: (2022)

Antidepressant-Like Effects and Cognitive Enhancement of Coadministration of Chaihu Shugan San and Fluoxetine: Dependent on the BDNF-ERK-CREB Signaling Pathway in the Hippocampus and Frontal Cortex
por: Yan, Lijing, et al.
Publicado: (2020)

Non-Alcoholic Fatty Liver Disease (NAFLD) and Its Connection with Insulin Resistance, Dyslipidemia, Atherosclerosis and Coronary Heart Disease
por: Gaggini, Melania, et al.
Publicado: (2013)

Effects of BDNF Polymorphisms on Antidepressant Action
por: Tsai, Shih-Jen, et al.
Publicado: (2010)

Treatment of Hypothyroid Patients With L-Thyroxine (L-T4) Plus Triiodothyronine Sulfate (T3S). A Phase II, Open-Label, Single Center, Parallel Groups Study on Therapeutic Efficacy and Tolerability
por: Santini, Ferruccio, et al.
Publicado: (2019)

An HDAC-dependent epigenetic mechanism that enhances the efficacy of the antidepressant drug fluoxetine
por: Schmauss, C.
Publicado: (2015)

Hippocampal MicroRNAs Respond to Administration of Antidepressant Fluoxetine in Adult Mice
por: Miao, Nan, et al.
Publicado: (2018)

The antidepressant fluoxetine induces necrosis by energy depletion and mitochondrial calcium overload
por: Charles, Emilie, et al.
Publicado: (2016)

Antidepressant effects of Kai-Xin-San in fluoxetine-resistant depression rats
por: Dong, X.Z., et al.
Publicado: (2017)

Transcriptomic evidence for immaturity induced by antidepressant fluoxetine in the hippocampus and prefrontal cortex
por: Hagihara, Hideo, et al.
Publicado: (2019)

Ketogenic Diet and Weight Loss: Is There an Effect on Energy Expenditure?
por: Basolo, Alessio, et al.
Publicado: (2022)

Fluoxetine, an antidepressant, suppresses glioblastoma by evoking AMPAR-mediated calcium-dependent apoptosis
por: Liu, Kao-Hui, et al.
Publicado: (2014)

The expression of platelet serotonin transporter (SERT) in human obesity
por: Giannaccini, Gino, et al.
Publicado: (2013)

The Roles of BDNF in the Pathophysiology of Major Depression and in Antidepressant Treatment
por: Lee, Bun-Hee, et al.
Publicado: (2010)

Neurogenomic Evidence for a Shared Mechanism of the Antidepressant Effects of Exercise and Chronic Fluoxetine in Mice
por: Huang, Guo-Jen, et al.
Publicado: (2012)

Does Curcumin or Pindolol Potentiate Fluoxetine's Antidepressant Effect by a Pharmacokinetic or Pharmacodynamic Interaction?
por: Murad, H.A.S., et al.
Publicado: (2014)

Requirement of hippocampal DG nNOS-CAPON dissociation for the anxiolytic and antidepressant effects of fluoxetine
por: Shi, Hu-Jiang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_61q9f9hnfcven9g09itpfgjhch