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The transcriptional response to oxidative stress is part of, but not sufficient for, insulin resistance in adipocytes
Insulin resistance is a major risk factor for metabolic diseases such as Type 2 diabetes. Although the underlying mechanisms of insulin resistance remain elusive, oxidative stress is a unifying driver by which numerous extrinsic signals and cellular stresses trigger insulin resistance. Consequently,...
Autores principales: | Chaudhuri, Rima, Krycer, James R., Fazakerley, Daniel J., Fisher-Wellman, Kelsey H., Su, Zhiduan, Hoehn, Kyle L., Yang, Jean Yee Hwa, Kuncic, Zdenka, Vafaee, Fatemeh, James, David E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789081/ https://www.ncbi.nlm.nih.gov/pubmed/29379070 http://dx.doi.org/10.1038/s41598-018-20104-x |
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