Mechanisms driving the antibacterial and antibiofilm properties of Hp1404 and its analogue peptides against multidrug-resistant Pseudomonas aeruginosa

Hp1404, identified from the venom of the scorpion Heterometrus petersii, displays antimicrobial activity with cytotoxicity. Several synthetic peptides were designed based on the parent peptide Hp1404 to reduce cytotoxicity and improve activity (deletion of glycine and phenylalanine, substitution wit...

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Detalles Bibliográficos
Autores principales: Kim, Min Kyung, Kang, Hee Kyoung, Ko, Su Jin, Hong, Min Ji, Bang, Jeong Kyu, Seo, Chang Ho, Park, Yoonkyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789083/
https://www.ncbi.nlm.nih.gov/pubmed/29379033
http://dx.doi.org/10.1038/s41598-018-19434-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789083/
https://www.ncbi.nlm.nih.gov/pubmed/29379033
http://dx.doi.org/10.1038/s41598-018-19434-7

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