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An MCEM Framework for Drug Safety Signal Detection and Combination from Heterogeneous Real World Evidence
Delayed drug safety insights can impact patients, pharmaceutical companies, and the whole society. Post-market drug safety surveillance plays a critical role in providing drug safety insights, where real world evidence such as spontaneous reporting systems (SRS) and a series of disproportional analy...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789130/ https://www.ncbi.nlm.nih.gov/pubmed/29379048 http://dx.doi.org/10.1038/s41598-018-19979-7 |