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Protein Kinase A Distribution Differentiates Human Glioblastoma from Brain Tissue

Brain tumor glioblastoma has no clear molecular signature and there is no effective therapy. In rodents, the intracellular distribution of the cyclic AMP (cAMP)-dependent protein kinase (Protein kinase A, PKA) R2Alpha subunit was previously shown to differentiate tumor cells from healthy brain cells...

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Detalles Bibliográficos
Autores principales: Mucignat-Caretta, Carla, Denaro, Luca, D’Avella, Domenico, Caretta, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789352/
https://www.ncbi.nlm.nih.gov/pubmed/29267253
http://dx.doi.org/10.3390/cancers10010002