Maturation of hematopoietic stem cells from prehematopoietic stem cells is accompanied by up-regulation of PD-L1

Hematopoietic stem cells (HSCs) mature from pre-HSCs that originate in the major arteries of the embryo. To identify HSCs from in vitro sources, it will be necessary to refine markers of HSCs matured ex vivo. We purified and compared the transcriptomes of pre-HSCs, HSCs matured ex vivo, and fetal li...

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Detalles Bibliográficos
Autores principales: Tober, Joanna, Maijenburg, Marijke M.W., Li, Yan, Gao, Long, Hadland, Brandon K., Gao, Peng, Minoura, Kodai, Bernstein, Irwin D., Tan, Kai, Speck, Nancy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789403/
https://www.ncbi.nlm.nih.gov/pubmed/29282253
http://dx.doi.org/10.1084/jem.20161594

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