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Iron modulation of erythropoiesis is associated with Scribble-mediated control of the erythropoietin receptor

Iron-restricted human anemias are associated with the acquisition of marrow resistance to the hematopoietic cytokine erythropoietin (Epo). Regulation of Epo responsiveness by iron availability serves as the basis for intravenous iron therapy in anemias of chronic disease. Epo engagement of its recep...

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Detalles Bibliográficos
Autores principales: Khalil, Shadi, Delehanty, Lorrie, Grado, Stephen, Holy, Maja, White, Zollie, Freeman, Katie, Kurita, Ryo, Nakamura, Yukio, Bullock, Grant, Goldfarb, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789406/
https://www.ncbi.nlm.nih.gov/pubmed/29282252
http://dx.doi.org/10.1084/jem.20170396