Obesity alters the long-term fitness of the hematopoietic stem cell compartment through modulation of Gfi1 expression

Obesity is a chronic organismal stress that disrupts multiple systemic and tissue-specific functions. In this study, we describe the impact of obesity on the activity of the hematopoietic stem cell (HSC) compartment. We show that obesity alters the composition of the HSC compartment and its activity...

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Detalles Bibliográficos
Autores principales: Lee, Jung-Mi, Govindarajah, Vinothini, Goddard, Bryan, Hinge, Ashwini, Muench, David E., Filippi, Marie-Dominique, Aronow, Bruce, Cancelas, Jose A., Salomonis, Nathan, Grimes, H. Leighton, Reynaud, Damien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789409/
https://www.ncbi.nlm.nih.gov/pubmed/29282250
http://dx.doi.org/10.1084/jem.20170690

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