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Ablation of endothelial VEGFR1 improves metabolic dysfunction by inducing adipose tissue browning
Angiogenesis plays an instrumental role in the modulation of adipose tissue mass and metabolism. Targeting adipose vasculature provides an outstanding opportunity for treatment of obesity and metabolic disorders. Here, we report the physiological functions of VEGFR1 in the modulation of adipose angi...
Autores principales: | Seki, Takahiro, Hosaka, Kayoko, Fischer, Carina, Lim, Sharon, Andersson, Patrik, Abe, Mitsuhiko, Iwamoto, Hideki, Gao, Yanyan, Wang, Xinsheng, Fong, Guo-Hua, Cao, Yihai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789413/ https://www.ncbi.nlm.nih.gov/pubmed/29305395 http://dx.doi.org/10.1084/jem.20171012 |
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