Cargando…
Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors
Multipotent hematopoietic progenitors must acquire thymus-homing capacity to initiate T lymphocyte development. Despite its importance, the transcriptional program underlying this process remains elusive. Cbfβ forms transcription factor complexes with Runx proteins, and here we show that Cbfβ2, enco...
Autores principales: | Tenno, Mari, Kojo, Satoshi, Lawir, Divine-Fondzenyuy, Hess, Isabell, Shiroguchi, Katsuyuki, Ebihara, Takashi, Endo, Takaho A., Muroi, Sawako, Satoh, Rumi, Kawamoto, Hiroshi, Boehm, Thomas, Taniuchi, Ichiro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789415/ https://www.ncbi.nlm.nih.gov/pubmed/29343500 http://dx.doi.org/10.1084/jem.20171221 |
Ejemplares similares
-
Cbfβ2 deficiency preserves Langerhans cell precursors by lack of selective TGFβ receptor signaling
por: Tenno, Mari, et al.
Publicado: (2017) -
Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation
por: Miyamoto, Chizuko, et al.
Publicado: (2019) -
Author Correction: Runx/Cbfβ complexes protect group 2 innate lymphoid cells from exhausted-like hyporesponsiveness during allergic airway inflammation
por: Miyamoto, Chizuko, et al.
Publicado: (2019) -
Runx-dependent and silencer-independent repression of a maturation enhancer in the Cd4 gene
por: Kojo, Satoshi, et al.
Publicado: (2018) -
Evolutionary transition from degenerate to nonredundant cytokine signaling networks supporting intrathymic T cell development
por: Lawir, Divine-Fondzenyuy, et al.
Publicado: (2019)