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Cardiac macrophages promote diastolic dysfunction
Macrophages populate the healthy myocardium and, depending on their phenotype, may contribute to tissue homeostasis or disease. Their origin and role in diastolic dysfunction, a hallmark of cardiac aging and heart failure with preserved ejection fraction, remain unclear. Here we show that cardiac ma...
Autores principales: | Hulsmans, Maarten, Sager, Hendrik B., Roh, Jason D., Valero-Muñoz, María, Houstis, Nicholas E., Iwamoto, Yoshiko, Sun, Yuan, Wilson, Richard M., Wojtkiewicz, Gregory, Tricot, Benoit, Osborne, Michael T., Hung, Judy, Vinegoni, Claudio, Naxerova, Kamila, Sosnovik, David E., Zile, Michael R., Bradshaw, Amy D., Liao, Ronglih, Tawakol, Ahmed, Weissleder, Ralph, Rosenzweig, Anthony, Swirski, Filip K., Sam, Flora, Nahrendorf, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789416/ https://www.ncbi.nlm.nih.gov/pubmed/29339450 http://dx.doi.org/10.1084/jem.20171274 |
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