A fluorescent activatable probe for imaging intracellular Mg(2+) 

An activatable BODIPY probe for in vitro detection and fluorescence cell imaging of free Mg(2+) without interference from Ca(2+) is described. Fluorescence amplification of the probe is observed upon detection of physiological concentrations of Mg(2+) due to reduced rotation of the fluorophore and e...

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Detalles Bibliográficos
Autores principales: Treadwell, Ryan, de Moliner, Fabio, Subiros-Funosas, Ramon, Hurd, Toby, Knox, Kirsten, Vendrell, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789582/
https://www.ncbi.nlm.nih.gov/pubmed/29256562
http://dx.doi.org/10.1039/c7ob02965a
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author Treadwell, Ryan
de Moliner, Fabio
Subiros-Funosas, Ramon
Hurd, Toby
Knox, Kirsten
Vendrell, Marc
author_facet Treadwell, Ryan
de Moliner, Fabio
Subiros-Funosas, Ramon
Hurd, Toby
Knox, Kirsten
Vendrell, Marc
author_sort Treadwell, Ryan
collection PubMed
description An activatable BODIPY probe for in vitro detection and fluorescence cell imaging of free Mg(2+) without interference from Ca(2+) is described. Fluorescence amplification of the probe is observed upon detection of physiological concentrations of Mg(2+) due to reduced rotation of the fluorophore and effective chelation by a quinolizine-based core.
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spelling pubmed-57895822018-02-15 A fluorescent activatable probe for imaging intracellular Mg(2+)  Treadwell, Ryan de Moliner, Fabio Subiros-Funosas, Ramon Hurd, Toby Knox, Kirsten Vendrell, Marc Org Biomol Chem Chemistry An activatable BODIPY probe for in vitro detection and fluorescence cell imaging of free Mg(2+) without interference from Ca(2+) is described. Fluorescence amplification of the probe is observed upon detection of physiological concentrations of Mg(2+) due to reduced rotation of the fluorophore and effective chelation by a quinolizine-based core. Royal Society of Chemistry 2018-01-14 2017-12-19 /pmc/articles/PMC5789582/ /pubmed/29256562 http://dx.doi.org/10.1039/c7ob02965a Text en This journal is © The Royal Society of Chemistry 2018 http://creativecommons.org/licenses/by/3.0/ This article is freely available. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (CC BY 3.0)
spellingShingle Chemistry
Treadwell, Ryan
de Moliner, Fabio
Subiros-Funosas, Ramon
Hurd, Toby
Knox, Kirsten
Vendrell, Marc
A fluorescent activatable probe for imaging intracellular Mg(2+) 
title A fluorescent activatable probe for imaging intracellular Mg(2+) 
title_full A fluorescent activatable probe for imaging intracellular Mg(2+) 
title_fullStr A fluorescent activatable probe for imaging intracellular Mg(2+) 
title_full_unstemmed A fluorescent activatable probe for imaging intracellular Mg(2+) 
title_short A fluorescent activatable probe for imaging intracellular Mg(2+) 
title_sort fluorescent activatable probe for imaging intracellular mg(2+) 
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789582/
https://www.ncbi.nlm.nih.gov/pubmed/29256562
http://dx.doi.org/10.1039/c7ob02965a
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