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Piperine ameliorates SCA17 neuropathology by reducing ER stress

BACKGROUND: Spinocerebellar ataxia 17 (SCA17) belongs to the family of neurodegenerative diseases caused by polyglutamine (polyQ) expansion. In SCA17, polyQ expansion occurs in the TATA box binding protein (TBP) and leads to the misfolding of TBP and the preferential degeneration in the cerebellar P...

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Detalles Bibliográficos
Autores principales:	Guo, Jifeng, Cui, Yiting, Liu, Qiong, Yang, Yang, Li, Yujing, Weng, Ling, Tang, Beisha, Jin, Peng, Li, Xiao-Jiang, Yang, Su, Li, Shihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789626/ https://www.ncbi.nlm.nih.gov/pubmed/29378605 http://dx.doi.org/10.1186/s13024-018-0236-x

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