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Modulation of mitochondrial activity in HaCaT keratinocytes by the cell penetrating peptide Z-Gly-RGD(DPhe)-mitoparan

OBJECTIVE: Biologically active cell penetrating peptides (CPPs) are an emerging class of therapeutic agent. The wasp venom peptide mastoparan is an established CPP that modulates mitochondrial activity and triggers caspase-dependent apoptosis in cancer cells, as does the mastoparan analogue mitopara...

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Detalles Bibliográficos
Autores principales: Richardson, Adam, Muir, Lewis, Mousdell, Sasha, Sexton, Darren, Jones, Sarah, Howl, John, Ross, Kehinde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789630/
https://www.ncbi.nlm.nih.gov/pubmed/29378648
http://dx.doi.org/10.1186/s13104-018-3192-1