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Identification of novel candidate genes for 46,XY disorders of sex development (DSD) using a C57BL/6J-Y(POS) mouse model
BACKGROUND: Disorders of sex development (DSD) have an estimated frequency of 0.5% of live births encompassing a variety of urogenital anomalies ranging from mild hypospadias to a discrepancy between sex chromosomes and external genitalia. In order to identify the underlying genetic etiology, we had...
Autores principales: | Barseghyan, Hayk, Symon, Aleisha, Zadikyan, Mariam, Almalvez, Miguel, Segura, Eva E., Eskin, Ascia, Bramble, Matthew S., Arboleda, Valerie A., Baxter, Ruth, Nelson, Stanley F., Délot, Emmanuèle C., Harley, Vincent, Vilain, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789682/ https://www.ncbi.nlm.nih.gov/pubmed/29378665 http://dx.doi.org/10.1186/s13293-018-0167-9 |
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