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An integrative functional genomics framework for effective identification of novel regulatory variants in genome–phenome studies
BACKGROUND: Genome–phenome studies have identified thousands of variants that are statistically associated with disease or traits; however, their functional roles are largely unclear. A comprehensive investigation of regulatory mechanisms and the gene regulatory networks between phenome-wide associa...
Autores principales: | Zhao, Junfei, Cheng, Feixiong, Jia, Peilin, Cox, Nancy, Denny, Joshua C., Zhao, Zhongming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789733/ https://www.ncbi.nlm.nih.gov/pubmed/29378629 http://dx.doi.org/10.1186/s13073-018-0513-x |
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