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Adjuvant chemotherapy with or without bevacizumab in patients with resected non-small-cell lung cancer (E1505): an open-label, multicentre, randomised, phase 3 trial
BACKGROUND: Adjuvant chemotherapy for resected early stage NSCLC provides modest survival benefit. Bevacizumab, a monoclonal antibody directed against vascular endothelial growth factor, improves outcomes when added to platinum-based chemotherapy in advanced stage non-squamous NSCLC. We conducted a...
Autores principales: | Wakelee, Heather A., Dahlberg, Suzanne E., Keller, Steven M., Tester, William J., Gandara, David R., Graziano, Stephen L., Adjei, Alex, Leighl, Natasha B., Aisner, Seena C., Rothman, Jan M., Patel, Jyoti D., Sborov, Mark D., McDermott, Sean R., Perez-Soler, Roman, Traynor, Anne M., Butts, Charles, Evans, Tracey, Shafqat, Atif, Chapman, Andrew E., Kasbari, Samer S., Horn, Leora, Ramalingam, Suresh S., Schiller, Joan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789803/ https://www.ncbi.nlm.nih.gov/pubmed/29129443 http://dx.doi.org/10.1016/S1470-2045(17)30691-5 |
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