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Cardiogenic programming of human pluripotent stem cells by dose-controlled activation of EOMES

Master cell fate determinants are thought to induce specific cell lineages in gastrulation by orchestrating entire gene programs. The T-box transcription factor EOMES (eomesodermin) is crucially required for the development of the heart—yet it is equally important for endoderm specification suggesti...

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Detalles Bibliográficos
Autores principales:	Pfeiffer, Martin J., Quaranta, Roberto, Piccini, Ilaria, Fell, Jakob, Rao, Jyoti, Röpke, Albrecht, Seebohm, Guiscard, Greber, Boris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789885/ https://www.ncbi.nlm.nih.gov/pubmed/29382828 http://dx.doi.org/10.1038/s41467-017-02812-6

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