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miR-106b-5p promotes stem cell-like properties of hepatocellular carcinoma cells by targeting PTEN via PI3K/Akt pathway

BACKGROUND: The miRNA miR-106b-5p has been previously reported to be increased in hepatocellular carcinoma (HCC) tissues compared to cirrhotic tissues. The purpose of this study was to detect its expression in HCC cell lines with distinct metastatic potentials and to explore the molecular mechanisms...

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Detalles Bibliográficos
Autores principales: Shi, Dong-Min, Bian, Xin-Yu, Qin, Cheng-Dong, Wu, Wei-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790077/
https://www.ncbi.nlm.nih.gov/pubmed/29416358
http://dx.doi.org/10.2147/OTT.S152611