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Decoding the network of Trypanosoma brucei proteins that determines sensitivity to apolipoprotein-L1

In contrast to Trypanosoma brucei gambiense and T. b. rhodesiense (the causative agents of human African trypanosomiasis), T. b. brucei is lysed by apolipoprotein-L1 (apoL1)-containing human serum trypanolytic factors (TLF), rendering it non-infectious to humans. While the mechanisms of TLF1 uptake,...

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Detalles Bibliográficos
Autores principales: Currier, Rachel B., Cooper, Anneli, Burrell-Saward, Hollie, MacLeod, Annette, Alsford, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790291/
https://www.ncbi.nlm.nih.gov/pubmed/29346416
http://dx.doi.org/10.1371/journal.ppat.1006855