Cargando…
Decoding the network of Trypanosoma brucei proteins that determines sensitivity to apolipoprotein-L1
In contrast to Trypanosoma brucei gambiense and T. b. rhodesiense (the causative agents of human African trypanosomiasis), T. b. brucei is lysed by apolipoprotein-L1 (apoL1)-containing human serum trypanolytic factors (TLF), rendering it non-infectious to humans. While the mechanisms of TLF1 uptake,...
Autores principales: | Currier, Rachel B., Cooper, Anneli, Burrell-Saward, Hollie, MacLeod, Annette, Alsford, Sam |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790291/ https://www.ncbi.nlm.nih.gov/pubmed/29346416 http://dx.doi.org/10.1371/journal.ppat.1006855 |
Ejemplares similares
-
Ornithine uptake and the modulation of drug sensitivity in Trypanosoma brucei
por: Macedo, Juan P., et al.
Publicado: (2017) -
Cathepsin-L Can Resist Lysis by Human Serum in Trypanosoma brucei brucei
por: Alsford, Sam, et al.
Publicado: (2014) -
Subverting lysosomal function in Trypanosoma brucei
por: Alsford, Sam
Publicado: (2015) -
Highly Sensitive In Vivo Imaging of Trypanosoma brucei Expressing “Red-Shifted” Luciferase
por: McLatchie, Alex P., et al.
Publicado: (2013) -
A Primate APOL1 Variant That Kills Trypanosoma brucei gambiense
por: Cooper, Anneli, et al.
Publicado: (2016)