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A Virus-Like-Particle immunotherapy targeting Epitope-Specific anti-xCT expressed on cancer stem cell inhibits the progression of metastatic cancer in vivo
Aggressive forms of breast cancer, such as Her2(+) and triple negative breast cancer (TNBC), are enriched in breast cancer stem cells (BCSC) and have limited therapeutic options. BCSC represent a key cellular reservoir for relapse, metastatic progression and therapeutic resistance. Their ability to...
Autores principales: | Bolli, Elisabetta, O'Rourke, John P., Conti, Laura, Lanzardo, Stefania, Rolih, Valeria, Christen, Jayne M., Barutello, Giuseppina, Forni, Marco, Pericle, Federica, Cavallo, Federica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790338/ https://www.ncbi.nlm.nih.gov/pubmed/29399412 http://dx.doi.org/10.1080/2162402X.2017.1408746 |
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