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T cells specific for a TAP-independent self-peptide remain naïve in tumor-bearing mice and are fully exploitable for therapy
Cancers frequently evade immune-recognition by lowering peptide:MHC-I complexes on their cell surface. Limited peptide supply due to TAP-deficiency results in such MHC-I(low) immune-escape variants. Previously, we reported on a category of TAP-independent self-peptides, called TEIPP, with selective...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790395/ https://www.ncbi.nlm.nih.gov/pubmed/29399388 http://dx.doi.org/10.1080/2162402X.2017.1382793 |