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Role of ZNF224 in c-Myc repression and imatinib responsiveness in chronic myeloid leukemia

The transcription factor ZNF224 plays a key proapoptotic role in chronic myelogenous leukemia (CML), by modulating Wilms Tumor protein 1 (WT1) dependent apoptotic genes transcription. Recently, we demonstrated that Bcr-Abl signaling represses ZNF224 expression in Bcr-Abl positive CML cell lines and...

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Detalles Bibliográficos
Autores principales:	Sodaro, Gaetano, Cesaro, Elena, Montano, Giorgia, Blasio, Giancarlo, Fiorentino, Federica, Romano, Simona, Jacquel, Arnaud, Aurberger, Patrick, Costanzo, Paola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790473/ https://www.ncbi.nlm.nih.gov/pubmed/29423056 http://dx.doi.org/10.18632/oncotarget.23283

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