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Drug-induced ciliogenesis in pancreatic cancer cells is facilitated by the secreted ATP-purinergic receptor signaling pathway

Malignant transformation of cells is often accompanied by the loss of the primary cilium, a protruding microtubule-based sensory organelle, suggesting that it plays an “onco-suppressive” role. Therefore, restoration of the primary cilium is being explored as a new therapeutic approach to attenuate t...

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Detalles Bibliográficos
Autores principales: Khan, Niamat Ali, Garg, Abhishek D., Agostinis, Patrizia, Swinnen, Johannes V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790479/
https://www.ncbi.nlm.nih.gov/pubmed/29423062
http://dx.doi.org/10.18632/oncotarget.23335