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Interferon β protects against avascular osteonecrosis through interleukin 6 inhibition and silent information regulator transcript-1 upregulation

Synovitis of the affected joint is a common in avascular osteonecrosis (AVN). Increased levels of pro-inflammatory cytokine interleukin-6 (IL-6) have been reported in AVN, but the mechanism of this increase remains unclear. Silent information regulator transcript-1 (SIRT1), an NAD-dependent deacetyl...

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Detalles Bibliográficos
Autores principales:	Kim, Kyoung Min, Wagle, Sajeev, Moon, Young Jae, Wang, Sung Il, Park, Byung-Hyun, Jang, Kyu Yun, Kim, Jung Ryul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790483/ https://www.ncbi.nlm.nih.gov/pubmed/29423066 http://dx.doi.org/10.18632/oncotarget.23337

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