Metformin induces distinct bioenergetic and metabolic profiles in sensitive versus resistant high grade serous ovarian cancer and normal fallopian tube secretory epithelial cells

Metformin is a widely used agent for the treatment of diabetes and infertility, however, it has been found to have anti-cancer effects in a variety of malignancies including high grade serous ovarian cancer (HGSC). Studies describing the mechanisms by which metformin affects HGSC are ongoing, but de...

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Detalles Bibliográficos
Autores principales: Hodeib, Melissa, Ogrodzinski, Martin P., Vergnes, Laurent, Reue, Karen, Karlan, Beth Y., Lunt, Sophia Y., Aspuria, Paul-Joseph P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790520/
https://www.ncbi.nlm.nih.gov/pubmed/29423103
http://dx.doi.org/10.18632/oncotarget.23661

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