Cancer immunogenomic approach to neoantigen discovery in a checkpoint blockade responsive murine model of oral cavity squamous cell carcinoma

Head and neck squamous cell carcinomas (HNSCC) are an ideal immunotherapy target due to their high mutation burden and frequent infiltration with lymphocytes. Preclinical models to investigate targeted and combination therapies as well as defining biomarkers to guide treatment represent an important...

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Detalles Bibliográficos
Autores principales: Zolkind, Paul, Przybylski, Dariusz, Marjanovic, Nemanja, Nguyen, Lan, Lin, Tianxiang, Johanns, Tanner, Alexandrov, Anton, Zhou, Liye, Allen, Clint T., Miceli, Alexander P., Schreiber, Robert D., Artyomov, Maxim, Dunn, Gavin P., Uppaluri, Ravindra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790525/
https://www.ncbi.nlm.nih.gov/pubmed/29423108
http://dx.doi.org/10.18632/oncotarget.23751

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