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HLA class I loss and PD-L1 expression in lung cancer: impact on T-cell infiltration and immune escape
Immune-checkpoint inhibitors show encouraging results in cancer treatment, but the clinical benefit is limited exclusively to a subset of patients. We analyzed the density and composition of tumor T-cell infiltration in non-small-cell lung carcinoma (NSCLC) in relation to PD-L1 and HLA class I (HLA-...
Autores principales: | Perea, Francisco, Sánchez-Palencia, Abel, Gómez-Morales, Mercedes, Bernal, Mónica, Concha, Ángel, García, Míguela Méndez, González-Ramírez, Amanda Rocío, Kerick, Martin, Martin, Javier, Garrido, Federico, Ruiz-Cabello, Francisco, Aptsiauri, Natalia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790526/ https://www.ncbi.nlm.nih.gov/pubmed/29423109 http://dx.doi.org/10.18632/oncotarget.23469 |
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