Cargando…

Ophiopogonin B sensitizes TRAIL-induced apoptosis through activation of autophagy flux and downregulates cellular FLICE-like inhibitory protein

Tumor necrosis factor related apoptosis-inducing ligand (TRAIL), a type II transmembrane protein, belongs to the TNF superfamily. Compared to other family members, TRAIL is a promising anti-cancer agent that can selectively induce apoptosis of various types of transformed cells and xenografts, with...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nazim, Uddin MD., Jeong, Jae-Kyo, Park, Sang-Youel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790529/ https://www.ncbi.nlm.nih.gov/pubmed/29423112 http://dx.doi.org/10.18632/oncotarget.23647

Ejemplares similares

Activation of autophagy flux by metformin downregulates cellular FLICE–like inhibitory protein and enhances TRAIL- induced apoptosis
por: Nazim, Uddin MD, et al.
Publicado: (2016)

Downregulation of c-FLIP and upregulation of DR-5 by cantharidin sensitizes TRAIL-mediated apoptosis in prostate cancer cells via autophagy flux
por: Nazim, Uddin Md, et al.
Publicado: (2020)

Attenuation of autophagy flux by 6-shogaol sensitizes human liver cancer cells to TRAIL-induced apoptosis via p53 and ROS
por: Nazim, Uddin MD., et al.
Publicado: (2019)

Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL-induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species
por: Nazim, Uddin Md, et al.
Publicado: (2019)

PPARγ activation by troglitazone enhances human lung cancer cells to TRAIL-induced apoptosis via autophagy flux
por: Nazim, Uddin MD., et al.
Publicado: (2017)

Neferine treatment enhances the TRAIL-induced apoptosis of human prostate cancer cells via autophagic flux and the JNK pathway
por: Nazim, Uddin Md, et al.
Publicado: (2020)

Glipizide sensitizes lung cancer cells to TRAIL-induced apoptosis via Akt/mTOR/autophagy pathways
por: Nazim, Uddin MD., et al.
Publicado: (2017)

Niacin alleviates TRAIL-mediated colon cancer cell death via autophagy flux activation
por: Kim, Sung-Wook, et al.
Publicado: (2015)

Cellular FLICE-inhibitory protein is required for T cell survival and cycling
por: Chau, Hien, et al.
Publicado: (2005)

Enhancement of TRAIL-induced apoptosis by 5-fluorouracil requires activating Bax and p53 pathways in TRAIL-resistant lung cancers
por: Nazim, Uddin MD., et al.
Publicado: (2017)

Immune Escape of Tumors in Vivo by Expression of Cellular Flice-Inhibitory Protein
por: Medema, Jan Paul, et al.
Publicado: (1999)

Association of TRAF2 with the short form of cellular FLICE-like inhibitory protein prevents TNFR1-mediated apoptosis
por: Kim, Dong-Joon, et al.
Publicado: (2008)

Mouse Lung Fibroblast Resistance to Fas-Mediated Apoptosis Is Dependent on the Baculoviral Inhibitor of Apoptosis Protein 4 and the Cellular FLICE-Inhibitory Protein
por: Predescu, Sanda A., et al.
Publicado: (2017)

Flice-Inhibitory Protein Is a Key Regulator of Germinal Center B Cell Apoptosis
por: Hennino, Ana, et al.
Publicado: (2001)

Sensitizing TRAIL-resistant A549 lung cancer cells and enhancing TRAIL-induced apoptosis with the antidepressant amitriptyline
por: Zinnah, K.M.A., et al.
Publicado: (2021)

Inhibition of autophagy flux by sertraline attenuates TRAIL resistance in lung cancer via death receptor 5 upregulation
por: Zinnah, Kazi Mohammad Ali, et al.
Publicado: (2020)

Flice-Inhibitory Protein Expression during Macrophage Differentiation Confers Resistance to FAS-Mediated Apoptosis
por: Perlman, Harris, et al.
Publicado: (1999)

Viral FLICE inhibitory protein of Rhesus monkey rhadinovirus inhibits apoptosis by enhancing autophagosome formation
por: Ritthipichai, Krit, et al.
Publicado: (2012)

Viral FLICE Inhibitory Protein of Rhesus Monkey Rhadinovirus Inhibits Apoptosis by Enhancing Autophagosome Formation
por: Ritthipichai, Krit, et al.
Publicado: (2012)

EGCG-mediated autophagy flux has a neuroprotection effect via a class III histone deacetylase in primary neuron cells
por: Lee, Ju-Hee, et al.
Publicado: (2015)

Neuroprotective effect of cellular prion protein (PrPC) is related with activation of alpha7 nicotinic acetylcholine receptor (α7nAchR)-mediated autophagy flux
por: Jeong, Jae-Kyo, et al.
Publicado: (2015)

Induction of cellular prion protein (PrPc) under hypoxia inhibits apoptosis caused by TRAIL treatment
por: Park, Jin-Young, et al.
Publicado: (2015)

Rocaglamide overcomes tumor necrosis factor-related apoptosis-inducing ligand resistance in hepatocellular carcinoma cells by attenuating the inhibition of caspase-8 through cellular FLICE-like-inhibitory protein downregulation
por: LUAN, ZHOU, et al.
Publicado: (2015)

Activation of autophagic flux by epigallocatechin gallate mitigates TRAIL-induced tumor cell apoptosis via down-regulation of death receptors
por: Kim, Sung-Wook, et al.
Publicado: (2016)

Down-regulation of cellular FLICE-inhibitory protein (Long Form) contributes to apoptosis induced by Hsp90 inhibition in human lung cancer cells
por: Wang, Qilin, et al.
Publicado: (2012)

Lipopolysaccharide pretreatment inhibits LPS-induced human umbilical cord mesenchymal stem cell apoptosis via upregulating the expression of cellular FLICE-inhibitory protein
por: HOU, YU SEN, et al.
Publicado: (2015)

Human prion protein-induced autophagy flux governs neuron cell damage in primary neuron cells
por: Moon, Ji-Hong, et al.
Publicado: (2016)

AMPK Activation Mediated by Hinokitiol Inhibits Adipogenic Differentiation of Mesenchymal Stem Cells through Autophagy Flux
por: Lee, Ju-Hee, et al.
Publicado: (2018)

Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells
por: Huangfu, Jingru, et al.
Publicado: (2021)

Global metabolomic and lipidomic analysis reveals the potential mechanisms of hemolysis effect of Ophiopogonin D and Ophiopogonin D' in vivo
por: Xu, Huan-Hua, et al.
Publicado: (2021)

Effects of ophiopogonin B on the proliferation and apoptosis of SGC-7901 human gastric cancer cells
por: ZHANG, WEIYUE, et al.
Publicado: (2016)

Inhibition of Death Receptor Signaling by Flice-Inhibitory Protein as a Mechanism for Immune Escape of Tumors
por: French, Lars E., et al.
Publicado: (1999)

A new perspective of triptolide-associated hepatotoxicity: the relevance of NF-κB and NF-κB-mediated cellular FLICE-inhibitory protein
por: Yuan, Ziqiao, et al.
Publicado: (2020)

Downregulation of DcR3 sensitizes hepatocellular carcinoma cells to TRAIL-induced apoptosis
por: Liang, Chaojie, et al.
Publicado: (2017)

Mitogen-activated Protein Kinase Kinase Antagonized Fas-associated Death Domain Protein–mediated Apoptosis by Induced FLICE-inhibitory Protein Expression
por: Yeh, Jung-Hua, et al.
Publicado: (1998)

Expression levels of heat shock protein 27 and cellular FLICE-like inhibitory protein in prostate cancer correlate with Gleason score sum and pathologic stage
por: Lee, Seung Wook, et al.
Publicado: (2015)

FLIP (Flice-like inhibitory protein) suppresses cytoplasmic double-stranded-RNA-induced apoptosis and NF-κB and IRF3-mediated signaling
por: Handa, Priya, et al.
Publicado: (2011)

Overcoming Hypoxic-Resistance of Tumor Cells to TRAIL-Induced Apoptosis through Melatonin
por: Lee, You-Jin, et al.
Publicado: (2014)

The Inhibitor of Death Receptor Signaling, Flice-Inhibitory Protein Defines a New Class of Tumor Progression Factors
por: Djerbi, Mounira, et al.
Publicado: (1999)

Ophiopogonin B induces reactive oxygen species-dependent apoptosis through the Hippo pathway in nasopharyngeal carcinoma
por: Dong, Wenhui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_21sk8j4mb6ekbrsbso58arsug0