Cargando…

Meta-analysis of three genome-wide association studies identifies two loci that predict survival and treatment outcome in breast cancer

The majority of breast cancers are driven by the female hormone oestrogen via oestrogen receptor (ER) alpha. ER-positive patients are commonly treated with adjuvant endocrine therapy, however, resistance is a common occurrence and aside from ER-status, no unequivocal predictive biomarkers are curren...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khan, Sofia, Fagerholm, Rainer, Kadalayil, Latha, Tapper, William, Aittomäki, Kristiina, Liu, Jianjun, Blomqvist, Carl, Eccles, Diana, Nevanlinna, Heli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Meta-Analysis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790536/ https://www.ncbi.nlm.nih.gov/pubmed/29423119 http://dx.doi.org/10.18632/oncotarget.22747

Ejemplares similares

A Genome Wide Meta-Analysis Study for Identification of Common Variation Associated with Breast Cancer Prognosis
por: Rafiq, Sajjad, et al.
Publicado: (2014)

Polygenic risk score is associated with increased disease risk in 52 Finnish breast cancer families
por: Muranen, Taru A., et al.
Publicado: (2016)

Breast tumors from CHEK2 1100delC-mutation carriers: genomic landscape and clinical implications
por: Muranen, Taru A, et al.
Publicado: (2011)

Germline variation in ADAMTSL1 is associated with prognosis following breast cancer treatment in young women
por: Kadalayil, Latha, et al.
Publicado: (2017)

Comprehensive analysis of NuMA variation in breast cancer
por: Kilpivaara, Outi, et al.
Publicado: (2008)

Relationship of patients' age to histopathological features of breast tumours in BRCA1 and BRCA2 and mutation-negative breast cancer families
por: Eerola, Hannaleena, et al.
Publicado: (2005)

Histopathological features of breast tumours in BRCA1, BRCA2 and mutation-negative breast cancer families
por: Eerola, Hannaleena, et al.
Publicado: (2005)

Pathogenic Variant Spectrum in Breast Cancer Risk Genes in Finnish Patients
por: Nurmi, Anna K., et al.
Publicado: (2022)

High miR-30 Expression Associates with Improved Breast Cancer Patient Survival and Treatment Outcome
por: Jamshidi, Maral, et al.
Publicado: (2021)

FANCM c.5101C>T mutation associates with breast cancer survival and treatment outcome
por: Kiiski, Johanna I., et al.
Publicado: (2016)

Variants on the promoter region of PTEN affect breast cancer progression and patient survival
por: Heikkinen, Tuomas, et al.
Publicado: (2011)

RAD51, XRCC3, and XRCC2 mutation screening in Finnish breast cancer families
por: Pelttari, Liisa M, et al.
Publicado: (2015)

Improvement of Survival Rate for Patients with Hepatocellular Carcinoma Using Transarterial Chemoembolization in Combination with Three-Dimensional Conformal Radiation Therapy: A Meta-Analysis
por: Bai, Houqiao, et al.
Publicado: (2016)

Basal cytokeratins in breast tumours among BRCA1, BRCA2 and mutation-negative breast cancer families
por: Eerola, Hannaleena, et al.
Publicado: (2008)

Meta-analysis of epigenome-wide association studies of carotid intima-media thickness
por: Portilla-Fernández, Eliana, et al.
Publicado: (2021)

Risk associated with central catheters for malignant tumor patients: a systematic review and meta-analysis
por: Lv, Yajuan, et al.
Publicado: (2018)

Meta-analysis of the association between three microRNA polymorphisms and breast cancer susceptibility
por: Mu, Kun, et al.
Publicado: (2017)

Meta-analysis of differences in Constant-Murley scores for three mid-shaft clavicular fracture treatments
por: Jiang, Wei, et al.
Publicado: (2017)

Association between three VEGF polymorphisms and renal cell carcinoma susceptibility: a meta-analysis
por: Hou, Qi, et al.
Publicado: (2017)

Adoptive immunotherapy shows encouraging benefit on non-small cell lung cancer: a systematic review and meta-analysis
por: Zhao, Binghao, et al.
Publicado: (2017)

Elevated Serum Levels of NSE and S-100β Correlate with Increased Risk of Acute Cerebral Infarction in Asian Populations
por: Li, Ke, et al.
Publicado: (2015)

Association of three promoter polymorphisms in interleukin-10 gene with cancer susceptibility in the Chinese population: a meta-analysis
por: Wang, Ping, et al.
Publicado: (2017)

Use of three-dimensional printing in preoperative planning in orthopaedic trauma surgery: A systematic review and meta-analysis
por: Morgan, Catrin, et al.
Publicado: (2020)

Three-dimensional versus two-dimensional video-assisted hepatectomy for liver disease: a meta-analysis of clinical data
por: Zhang, Shumao, et al.
Publicado: (2020)

Thiazolidinediones versus metformin on improving abnormal liver enzymes in patients with type 2 diabetes mellitus: a meta-analysis
por: Xu, Chunmei, et al.
Publicado: (2018)

Meta-Analysis of Combination Therapy of Chinese Herbs Plus Interferon and Ribavirin in Patients with Chronic Hepatitis C
por: Wang, Jianjun, et al.
Publicado: (2016)

Meta-analysis of the incidence and risks of interstitial lung disease and QTc prolongation in non-small-cell lung cancer patients treated with ALK inhibitors
por: Lin, Liping, et al.
Publicado: (2017)

Integrated Analysis of Three Publicly Available Gene Expression Profiles Identified Genes and Pathways Associated with Clear Cell Renal Cell Carcinoma
por: Han, YuPing, et al.
Publicado: (2020)

Three-dimensional time-of-flight magnetic resonance angiography combined with high resolution T2-weighted imaging in preoperative evaluation of microvascular decompression
por: Liang, Chen, et al.
Publicado: (2022)

The prognostic significance of high/positive expression of cyclin B1 in patients with three common digestive cancers: a systematic review and meta-analysis
por: Wen, Yong, et al.
Publicado: (2017)

Bimekizumab for the treatment of moderate-to-severe plaque psoriasis: a meta-analysis of randomized clinical trials
por: Wang, Yuqian, et al.
Publicado: (2023)

Progression-free survival as a surrogate endpoint for overall survival in modern ovarian cancer trials: a meta-analysis
por: Sjoquist, Katrin M., et al.
Publicado: (2018)

Breast-Conserving Surgery or Mastectomy?: Impact on Survival
por: Christiansen, Peer, et al.
Publicado: (2022)

Prognostic Significance of Clinicopathological Factors Influencing Overall Survival and Event-Free Survival of Patients with Cervical Cancer: A Systematic Review and Meta-Analysis
por: Kang, Shengwei, et al.
Publicado: (2022)

ATM variants and cancer risk in breast cancer patients from Southern Finland
por: Tommiska, Johanna, et al.
Publicado: (2006)

Effects of metformin on survival outcomes of pancreatic cancer: a meta-analysis
por: Dong, Yi-Wei, et al.
Publicado: (2017)

Predictors and mortality risk of venous thromboembolism in patients with COVID-19: systematic review and meta-analysis of observational studies
por: Agarwal, Gaurav, et al.
Publicado: (2022)

Metastatic potential and prognostic significance of SOX2: A meta-analysis
por: Javaeed, Arslaan, et al.
Publicado: (2019)

Neoadjuvant Chemoradiotherapy Improving Survival Outcomes for Esophageal Carcinoma: An Updated Meta-analysis
por: Wang, Dong-Bin, et al.
Publicado: (2016)

The impact of metformin use on survival in prostate cancer: a systematic review and meta-analysis
por: Xiao, Yao, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_0bi40d1q6f259h67pi89ohsbtl