Genome sequencing of two Bacillus anthracis strains: a virulent strain and a vaccinal strain

Bacillus anthracis strain SPV842_15 was isolated from bovine fetus, while B. anthracis strain Brazilian vaccinal was recovered from a commercial vaccine. We report here the genome sequences of both strains. The SPV842_15 genome is composed of a single circular chromosome with a length of 5,228,664 b...

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Autores principales: Siqueira, Franciele Maboni, Cibulski, Samuel Paulo, Mayer, Fabiana Quoos, Driemeier, David, Pavarini, Saulo Petinatti, Vargas, Agueda Palmira Castagna de
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Genome Announcement
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790590/
https://www.ncbi.nlm.nih.gov/pubmed/28807610
http://dx.doi.org/10.1016/j.bjm.2017.04.007
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author Siqueira, Franciele Maboni
Cibulski, Samuel Paulo
Mayer, Fabiana Quoos
Driemeier, David
Pavarini, Saulo Petinatti
Vargas, Agueda Palmira Castagna de
author_facet Siqueira, Franciele Maboni
Cibulski, Samuel Paulo
Mayer, Fabiana Quoos
Driemeier, David
Pavarini, Saulo Petinatti
Vargas, Agueda Palmira Castagna de
author_sort Siqueira, Franciele Maboni
collection PubMed
description Bacillus anthracis strain SPV842_15 was isolated from bovine fetus, while B. anthracis strain Brazilian vaccinal was recovered from a commercial vaccine. We report here the genome sequences of both strains. The SPV842_15 genome is composed of a single circular chromosome with a length of 5,228,664 base pairs, and comprises 5911 coding sequences. In turn, the Brazilian vaccinal genome remains in 201 contigs with 5733 coding sequences. Both genomes have an overall C + G content of 35.4%, and 11 genes encoding the ribosomal RNAs (rRNAs) 5S, 16S and 23S. Only the plasmid pX01 sequence, which carries genes for toxins synthesis, was detected and completely assembled for both strains. These plasmids have a length of 181,684 base pairs and a C + G content of 32.5%. These genomic data generate insights about vaccinal B. anthracis virulence.
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spelling pubmed-57905902018-01-31 Genome sequencing of two Bacillus anthracis strains: a virulent strain and a vaccinal strain Siqueira, Franciele Maboni Cibulski, Samuel Paulo Mayer, Fabiana Quoos Driemeier, David Pavarini, Saulo Petinatti Vargas, Agueda Palmira Castagna de Braz J Microbiol Genome Announcement Bacillus anthracis strain SPV842_15 was isolated from bovine fetus, while B. anthracis strain Brazilian vaccinal was recovered from a commercial vaccine. We report here the genome sequences of both strains. The SPV842_15 genome is composed of a single circular chromosome with a length of 5,228,664 base pairs, and comprises 5911 coding sequences. In turn, the Brazilian vaccinal genome remains in 201 contigs with 5733 coding sequences. Both genomes have an overall C + G content of 35.4%, and 11 genes encoding the ribosomal RNAs (rRNAs) 5S, 16S and 23S. Only the plasmid pX01 sequence, which carries genes for toxins synthesis, was detected and completely assembled for both strains. These plasmids have a length of 181,684 base pairs and a C + G content of 32.5%. These genomic data generate insights about vaccinal B. anthracis virulence. Elsevier 2017-07-31 /pmc/articles/PMC5790590/ /pubmed/28807610 http://dx.doi.org/10.1016/j.bjm.2017.04.007 Text en © 2017 Sociedade Brasileira de Microbiologia. Published by Elsevier Editora Ltda. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Genome Announcement
Siqueira, Franciele Maboni
Cibulski, Samuel Paulo
Mayer, Fabiana Quoos
Driemeier, David
Pavarini, Saulo Petinatti
Vargas, Agueda Palmira Castagna de
Genome sequencing of two Bacillus anthracis strains: a virulent strain and a vaccinal strain
title Genome sequencing of two Bacillus anthracis strains: a virulent strain and a vaccinal strain
title_full Genome sequencing of two Bacillus anthracis strains: a virulent strain and a vaccinal strain
title_fullStr Genome sequencing of two Bacillus anthracis strains: a virulent strain and a vaccinal strain
title_full_unstemmed Genome sequencing of two Bacillus anthracis strains: a virulent strain and a vaccinal strain
title_short Genome sequencing of two Bacillus anthracis strains: a virulent strain and a vaccinal strain
title_sort genome sequencing of two bacillus anthracis strains: a virulent strain and a vaccinal strain
topic Genome Announcement
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790590/
https://www.ncbi.nlm.nih.gov/pubmed/28807610
http://dx.doi.org/10.1016/j.bjm.2017.04.007
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