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Potential of RP-UHPLC-DAD-MS for the qualitative and quantitative analysis of sofosbuvir in film coated tablets and profiling degradants

Sofosbuvir is one of the new direct-acting antiviral drugs against hepatitis C virus (HCV) infection. This drug has recently been launched into the market, and generic versions of the medication are expected to be produced by local drug producers in some countries. Therefore, new methods are require...

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Detalles Bibliográficos
Autores principales: Contreras, María del Mar, Morales-Soto, Aránzazu, Segura-Carretero, Antonio, Valverde, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790698/
https://www.ncbi.nlm.nih.gov/pubmed/29404040
http://dx.doi.org/10.1016/j.jpha.2017.04.003