Occurrence of Dermatomyositis Immediately after Mastectomy Subsequent to Severe Chemotherapeutic Drug Eruption

We herein report a patient with breast cancer who developed dermatomyositis (DM) immediately after mastectomy. She had a history of severe drug eruption during neoadjuvant chemotherapy six months previously. Within a month after the operation, myalgia and rash, including Gottron's papules, deve...

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Autores principales: Otsuka, Yuki, Watanabe, Haruki, Kano, Yuzuki, Tatebe, Noriko, Sunahori-Watanabe, Katsue, Kawabata, Tomoko, Sada, Ken-ei, Wada, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790732/
https://www.ncbi.nlm.nih.gov/pubmed/29249766
http://dx.doi.org/10.2169/internalmedicine.9194-17
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author Otsuka, Yuki
Watanabe, Haruki
Kano, Yuzuki
Tatebe, Noriko
Sunahori-Watanabe, Katsue
Kawabata, Tomoko
Sada, Ken-ei
Wada, Jun
author_facet Otsuka, Yuki
Watanabe, Haruki
Kano, Yuzuki
Tatebe, Noriko
Sunahori-Watanabe, Katsue
Kawabata, Tomoko
Sada, Ken-ei
Wada, Jun
author_sort Otsuka, Yuki
collection PubMed
description We herein report a patient with breast cancer who developed dermatomyositis (DM) immediately after mastectomy. She had a history of severe drug eruption during neoadjuvant chemotherapy six months previously. Within a month after the operation, myalgia and rash, including Gottron's papules, developed, and skeletal-muscle enzymes elevated, so she was diagnosed with probable DM according to the Bohan and Peter criteria. In many neoplastic DM cases, the course of the disease parallels the course of the malignancy. Possible mechanisms were suggested to explain the development of DM in the present case and offer new insight into autoimmune diseases.
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spelling pubmed-57907322018-01-31 Occurrence of Dermatomyositis Immediately after Mastectomy Subsequent to Severe Chemotherapeutic Drug Eruption Otsuka, Yuki Watanabe, Haruki Kano, Yuzuki Tatebe, Noriko Sunahori-Watanabe, Katsue Kawabata, Tomoko Sada, Ken-ei Wada, Jun Intern Med Case Report We herein report a patient with breast cancer who developed dermatomyositis (DM) immediately after mastectomy. She had a history of severe drug eruption during neoadjuvant chemotherapy six months previously. Within a month after the operation, myalgia and rash, including Gottron's papules, developed, and skeletal-muscle enzymes elevated, so she was diagnosed with probable DM according to the Bohan and Peter criteria. In many neoplastic DM cases, the course of the disease parallels the course of the malignancy. Possible mechanisms were suggested to explain the development of DM in the present case and offer new insight into autoimmune diseases. The Japanese Society of Internal Medicine 2017-12-15 /pmc/articles/PMC5790732/ /pubmed/29249766 http://dx.doi.org/10.2169/internalmedicine.9194-17 Text en Copyright © 2017 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Otsuka, Yuki
Watanabe, Haruki
Kano, Yuzuki
Tatebe, Noriko
Sunahori-Watanabe, Katsue
Kawabata, Tomoko
Sada, Ken-ei
Wada, Jun
Occurrence of Dermatomyositis Immediately after Mastectomy Subsequent to Severe Chemotherapeutic Drug Eruption
title Occurrence of Dermatomyositis Immediately after Mastectomy Subsequent to Severe Chemotherapeutic Drug Eruption
title_full Occurrence of Dermatomyositis Immediately after Mastectomy Subsequent to Severe Chemotherapeutic Drug Eruption
title_fullStr Occurrence of Dermatomyositis Immediately after Mastectomy Subsequent to Severe Chemotherapeutic Drug Eruption
title_full_unstemmed Occurrence of Dermatomyositis Immediately after Mastectomy Subsequent to Severe Chemotherapeutic Drug Eruption
title_short Occurrence of Dermatomyositis Immediately after Mastectomy Subsequent to Severe Chemotherapeutic Drug Eruption
title_sort occurrence of dermatomyositis immediately after mastectomy subsequent to severe chemotherapeutic drug eruption
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790732/
https://www.ncbi.nlm.nih.gov/pubmed/29249766
http://dx.doi.org/10.2169/internalmedicine.9194-17
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