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Synthesis, isolation, identification and characterization of new process-related impurity in isoproterenol hydrochloride by HPLC, LC/ESI-MS and NMR

One unknown impurity (Imp-II) during the analysis of laboratory batches of isoproterenol hydrochloride was detected in the level ranging from 0.04% to 0.12% by high performance liquid chromatography with UV detection. The unknown impurity structure was proposed as 4-[2-(propan-2-ylamino)ethyl]benzen...

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Detalles Bibliográficos
Autores principales:	Kumar, Neeraj, Devineni, Subba Rao, Gajjala, Prasad Reddy, Dubey, Shailendra Kumar, Kumar, Pramod
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Xi'an Jiaotong University 2017
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790752/ https://www.ncbi.nlm.nih.gov/pubmed/29404065 http://dx.doi.org/10.1016/j.jpha.2017.05.002

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