Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly

Disease epidemiology during ageing shows a transition from cancer to degenerative chronic disorders as dominant contributors to mortality in the old. Nevertheless, it has remained unclear to what extent molecular signatures of ageing reflect this phenomenon. Here we report on the identification of a...

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Detalles Bibliográficos
Autores principales: Aramillo Irizar, Peer, Schäuble, Sascha, Esser, Daniela, Groth, Marco, Frahm, Christiane, Priebe, Steffen, Baumgart, Mario, Hartmann, Nils, Marthandan, Shiva, Menzel, Uwe, Müller, Jule, Schmidt, Silvio, Ast, Volker, Caliebe, Amke, König, Rainer, Krawczak, Michael, Ristow, Michael, Schuster, Stefan, Cellerino, Alessandro, Diekmann, Stephan, Englert, Christoph, Hemmerich, Peter, Sühnel, Jürgen, Guthke, Reinhard, Witte, Otto W., Platzer, Matthias, Ruppin, Eytan, Kaleta, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790807/
https://www.ncbi.nlm.nih.gov/pubmed/29382830
http://dx.doi.org/10.1038/s41467-017-02395-2

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