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Conditional Protein Splicing Switch in Hyperthermophiles through an Intein-Extein Partnership

Inteins are intervening proteins that undergo an autocatalytic splicing reaction that ligates flanking host protein sequences termed exteins. Some intein-containing proteins have evolved to couple splicing to environmental signals; this represents a new form of posttranslational regulation. Of parti...

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Detalles Bibliográficos
Autores principales: Lennon, Christopher W., Stanger, Matthew, Banavali, Nilesh K., Belfort, Marlene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790916/
https://www.ncbi.nlm.nih.gov/pubmed/29382734
http://dx.doi.org/10.1128/mBio.02304-17