Arginylglycylaspartic Acid-Surface-Functionalized Doxorubicin-Loaded Lipid-Core Nanocapsules as a Strategy to Target Alpha(V) Beta(3) Integrin Expressed on Tumor Cells

Doxorubicin (Dox) clinical use is limited by dose-related cardiomyopathy, becoming more prevalent with increasing cumulative doses. Previously, we developed Dox-loaded lipid-core nanocapsules (Dox-LNC) and, in this study, we hypothesized that self-assembling and interfacial reactions could be used t...

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Detalles Bibliográficos
Autores principales: Antonow, Michelli B., Franco, Camila, Prado, Willian, Beckenkamp, Aline, Silveira, Gustavo P., Buffon, Andréia, Guterres, Sílvia S., Pohlmann, Adriana R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791089/
https://www.ncbi.nlm.nih.gov/pubmed/29271920
http://dx.doi.org/10.3390/nano8010002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791089/
https://www.ncbi.nlm.nih.gov/pubmed/29271920
http://dx.doi.org/10.3390/nano8010002

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