CD1a on Langerhans cells controls inflammatory skin diseases

CD1a is a lipid-presenting molecule abundantly expressed on Langerhans cells. However, the in vivo role of CD1a remains unclear, principally because CD1a is lacking in mice. Using CD1a-transgenic mice, we show that the plant-derived lipid urushiol triggers CD1a-dependent skin inflammation, driven by...

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Detalles Bibliográficos
Autores principales: Kim, Ji Hyung, Hu, Yu, Yongqing, Tang, Kim, Jessica, Hughes, Victoria A., Nours, Jérôme Le, Marquez, Elsa A., Purcell, Anthony W., Wan, Qi, Sugita, Masahiko, Rossjohn, Jamie, Winau, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791155/
https://www.ncbi.nlm.nih.gov/pubmed/27548435
http://dx.doi.org/10.1038/ni.3523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791155/
https://www.ncbi.nlm.nih.gov/pubmed/27548435
http://dx.doi.org/10.1038/ni.3523

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