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Upregulation of HMGB1-TLR4 inflammatory pathway in focal cortical dysplasia type II

BACKGROUND: We attempted to determine whether the inflammatory pathway HMGB1-TLR4 and the downstream pro-inflammatory cytokines is upregulated in focal cortical dysplasia (FCD) type II and whether there is a correlation between the TLR4 upregulation and disease duration or frequency of epileptic sei...

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Detalles Bibliográficos
Autores principales: Zhang, Zhongbin, Liu, Qingzhu, Liu, Ming, Wang, Hui, Dong, Ying, Ji, Taoyun, Liu, Xiaoyan, Jiang, Yuwu, Cai, Lixin, Wu, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791174/
https://www.ncbi.nlm.nih.gov/pubmed/29382328
http://dx.doi.org/10.1186/s12974-018-1078-8