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miRNA-23a/CXCR4 regulates neuropathic pain via directly targeting TXNIP/NLRP3 inflammasome axis
BACKGROUND: Chemokine CXC receptor 4 (CXCR4) in spinal glial cells has been implicated in neuropathic pain. However, the regulatory cascades of CXCR4 in neuropathic pain remain elusive. Here, we investigated the functional regulatory role of miRNAs in the pain process and its interplay with CXCR4 an...
Autores principales: | Pan, Zhiqiang, Shan, Qun, Gu, Pan, Wang, Xiao Min, Tai, Lydia Wai, Sun, Menglan, Luo, Xin, Sun, Liting, Cheung, Chi Wai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791181/ https://www.ncbi.nlm.nih.gov/pubmed/29386025 http://dx.doi.org/10.1186/s12974-018-1073-0 |
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