Treatment of Middle East Respiratory Syndrome with a combination of lopinavir-ritonavir and interferon-β1b (MIRACLE trial): study protocol for a randomized controlled trial

BACKGROUND: It had been more than 5 years since the first case of Middle East Respiratory Syndrome coronavirus infection (MERS-CoV) was recorded, but no specific treatment has been investigated in randomized clinical trials. Results from in vitro and animal studies suggest that a combination of lopi...

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Detalles Bibliográficos
Autores principales: Arabi, Yaseen M., Alothman, Adel, Balkhy, Hanan H., Al-Dawood, Abdulaziz, AlJohani, Sameera, Al Harbi, Shmeylan, Kojan, Suleiman, Al Jeraisy, Majed, Deeb, Ahmad M., Assiri, Abdullah M., Al-Hameed, Fahad, AlSaedi, Asim, Mandourah, Yasser, Almekhlafi, Ghaleb A., Sherbeeni, Nisreen Murad, Elzein, Fatehi Elnour, Memon, Javed, Taha, Yusri, Almotairi, Abdullah, Maghrabi, Khalid A., Qushmaq, Ismael, Al Bshabshe, Ali, Kharaba, Ayman, Shalhoub, Sarah, Jose, Jesna, Fowler, Robert A., Hayden, Frederick G., Hussein, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791210/
https://www.ncbi.nlm.nih.gov/pubmed/29382391
http://dx.doi.org/10.1186/s13063-017-2427-0

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