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Effect of the addition of rocuronium to 2% lignocaine in peribulbar block for cataract surgery

BACKGROUND AND AIMS: Peribulbar anesthesia is associated with delayed orbital akinesia compared with retrobulbar anesthesia. To test the hypothesis that rocuronium added to a mixture of local anesthetics (LAs) could improve speed of onset of akinesia in peribulbar block (PB), we designed this study....

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Autores principales: Patil, Vishalakshi, Farooqy, Allauddin, Chaluvadi, Balaraju Thayappa, Rajashekhar, Vinayak, Malshetty, Ashwini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791268/
https://www.ncbi.nlm.nih.gov/pubmed/29416247
http://dx.doi.org/10.4103/joacp.JOACP_383_16
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author Patil, Vishalakshi
Farooqy, Allauddin
Chaluvadi, Balaraju Thayappa
Rajashekhar, Vinayak
Malshetty, Ashwini
author_facet Patil, Vishalakshi
Farooqy, Allauddin
Chaluvadi, Balaraju Thayappa
Rajashekhar, Vinayak
Malshetty, Ashwini
author_sort Patil, Vishalakshi
collection PubMed
description BACKGROUND AND AIMS: Peribulbar anesthesia is associated with delayed orbital akinesia compared with retrobulbar anesthesia. To test the hypothesis that rocuronium added to a mixture of local anesthetics (LAs) could improve speed of onset of akinesia in peribulbar block (PB), we designed this study. This study examined the effects of adding rocuronium 5 mg to 2% lignocaine with adrenaline to note orbital and eyelid akinesia in patients undergoing cataract surgery. MATERIAL AND METHODS: In a prospective, randomized, double-blind study, 100 patients were equally randomized to receive a mixture of 0.5 ml normal saline, 6 ml lidocaine 2% with adrenaline and hyaluronidase 50 IU/ml (Group I), a mixture of rocuronium 0.5 ml (5 mg), 6 ml lidocaine 2% with adrenaline and hyaluronidase 50 IU/ml (Group II). Orbital akinesia was assessed on a 0–8 score (0 = no movement, 8 = normal) at 2 min intervals for 10 min. Time to adequate anesthesia was also recorded. Results are presented as mean ± standard deviation. RESULTS: Rocuronium group demonstrated significantly better akinesia scores than control group at 2 min intervals post-PB (significant P value obtained). No significant complications were recorded. Rocuronium added to a mixture of LA improved the quality of akinesia in PB and reduced the need for supplementary injections. CONCLUSION: The addition of rocuronium 5 mg to a mixture of lidocaine 2% with adrenaline and hyaluronidase 50 IU/ml shortened the onset time of peribulbar anesthesia in patients undergoing cataract surgery without causing adverse effects.
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spelling pubmed-57912682018-02-07 Effect of the addition of rocuronium to 2% lignocaine in peribulbar block for cataract surgery Patil, Vishalakshi Farooqy, Allauddin Chaluvadi, Balaraju Thayappa Rajashekhar, Vinayak Malshetty, Ashwini J Anaesthesiol Clin Pharmacol Original Article BACKGROUND AND AIMS: Peribulbar anesthesia is associated with delayed orbital akinesia compared with retrobulbar anesthesia. To test the hypothesis that rocuronium added to a mixture of local anesthetics (LAs) could improve speed of onset of akinesia in peribulbar block (PB), we designed this study. This study examined the effects of adding rocuronium 5 mg to 2% lignocaine with adrenaline to note orbital and eyelid akinesia in patients undergoing cataract surgery. MATERIAL AND METHODS: In a prospective, randomized, double-blind study, 100 patients were equally randomized to receive a mixture of 0.5 ml normal saline, 6 ml lidocaine 2% with adrenaline and hyaluronidase 50 IU/ml (Group I), a mixture of rocuronium 0.5 ml (5 mg), 6 ml lidocaine 2% with adrenaline and hyaluronidase 50 IU/ml (Group II). Orbital akinesia was assessed on a 0–8 score (0 = no movement, 8 = normal) at 2 min intervals for 10 min. Time to adequate anesthesia was also recorded. Results are presented as mean ± standard deviation. RESULTS: Rocuronium group demonstrated significantly better akinesia scores than control group at 2 min intervals post-PB (significant P value obtained). No significant complications were recorded. Rocuronium added to a mixture of LA improved the quality of akinesia in PB and reduced the need for supplementary injections. CONCLUSION: The addition of rocuronium 5 mg to a mixture of lidocaine 2% with adrenaline and hyaluronidase 50 IU/ml shortened the onset time of peribulbar anesthesia in patients undergoing cataract surgery without causing adverse effects. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5791268/ /pubmed/29416247 http://dx.doi.org/10.4103/joacp.JOACP_383_16 Text en Copyright: © 2018 Journal of Anaesthesiology Clinical Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Patil, Vishalakshi
Farooqy, Allauddin
Chaluvadi, Balaraju Thayappa
Rajashekhar, Vinayak
Malshetty, Ashwini
Effect of the addition of rocuronium to 2% lignocaine in peribulbar block for cataract surgery
title Effect of the addition of rocuronium to 2% lignocaine in peribulbar block for cataract surgery
title_full Effect of the addition of rocuronium to 2% lignocaine in peribulbar block for cataract surgery
title_fullStr Effect of the addition of rocuronium to 2% lignocaine in peribulbar block for cataract surgery
title_full_unstemmed Effect of the addition of rocuronium to 2% lignocaine in peribulbar block for cataract surgery
title_short Effect of the addition of rocuronium to 2% lignocaine in peribulbar block for cataract surgery
title_sort effect of the addition of rocuronium to 2% lignocaine in peribulbar block for cataract surgery
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791268/
https://www.ncbi.nlm.nih.gov/pubmed/29416247
http://dx.doi.org/10.4103/joacp.JOACP_383_16
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