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Effect of the addition of rocuronium to 2% lignocaine in peribulbar block for cataract surgery
BACKGROUND AND AIMS: Peribulbar anesthesia is associated with delayed orbital akinesia compared with retrobulbar anesthesia. To test the hypothesis that rocuronium added to a mixture of local anesthetics (LAs) could improve speed of onset of akinesia in peribulbar block (PB), we designed this study....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791268/ https://www.ncbi.nlm.nih.gov/pubmed/29416247 http://dx.doi.org/10.4103/joacp.JOACP_383_16 |
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author | Patil, Vishalakshi Farooqy, Allauddin Chaluvadi, Balaraju Thayappa Rajashekhar, Vinayak Malshetty, Ashwini |
author_facet | Patil, Vishalakshi Farooqy, Allauddin Chaluvadi, Balaraju Thayappa Rajashekhar, Vinayak Malshetty, Ashwini |
author_sort | Patil, Vishalakshi |
collection | PubMed |
description | BACKGROUND AND AIMS: Peribulbar anesthesia is associated with delayed orbital akinesia compared with retrobulbar anesthesia. To test the hypothesis that rocuronium added to a mixture of local anesthetics (LAs) could improve speed of onset of akinesia in peribulbar block (PB), we designed this study. This study examined the effects of adding rocuronium 5 mg to 2% lignocaine with adrenaline to note orbital and eyelid akinesia in patients undergoing cataract surgery. MATERIAL AND METHODS: In a prospective, randomized, double-blind study, 100 patients were equally randomized to receive a mixture of 0.5 ml normal saline, 6 ml lidocaine 2% with adrenaline and hyaluronidase 50 IU/ml (Group I), a mixture of rocuronium 0.5 ml (5 mg), 6 ml lidocaine 2% with adrenaline and hyaluronidase 50 IU/ml (Group II). Orbital akinesia was assessed on a 0–8 score (0 = no movement, 8 = normal) at 2 min intervals for 10 min. Time to adequate anesthesia was also recorded. Results are presented as mean ± standard deviation. RESULTS: Rocuronium group demonstrated significantly better akinesia scores than control group at 2 min intervals post-PB (significant P value obtained). No significant complications were recorded. Rocuronium added to a mixture of LA improved the quality of akinesia in PB and reduced the need for supplementary injections. CONCLUSION: The addition of rocuronium 5 mg to a mixture of lidocaine 2% with adrenaline and hyaluronidase 50 IU/ml shortened the onset time of peribulbar anesthesia in patients undergoing cataract surgery without causing adverse effects. |
format | Online Article Text |
id | pubmed-5791268 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-57912682018-02-07 Effect of the addition of rocuronium to 2% lignocaine in peribulbar block for cataract surgery Patil, Vishalakshi Farooqy, Allauddin Chaluvadi, Balaraju Thayappa Rajashekhar, Vinayak Malshetty, Ashwini J Anaesthesiol Clin Pharmacol Original Article BACKGROUND AND AIMS: Peribulbar anesthesia is associated with delayed orbital akinesia compared with retrobulbar anesthesia. To test the hypothesis that rocuronium added to a mixture of local anesthetics (LAs) could improve speed of onset of akinesia in peribulbar block (PB), we designed this study. This study examined the effects of adding rocuronium 5 mg to 2% lignocaine with adrenaline to note orbital and eyelid akinesia in patients undergoing cataract surgery. MATERIAL AND METHODS: In a prospective, randomized, double-blind study, 100 patients were equally randomized to receive a mixture of 0.5 ml normal saline, 6 ml lidocaine 2% with adrenaline and hyaluronidase 50 IU/ml (Group I), a mixture of rocuronium 0.5 ml (5 mg), 6 ml lidocaine 2% with adrenaline and hyaluronidase 50 IU/ml (Group II). Orbital akinesia was assessed on a 0–8 score (0 = no movement, 8 = normal) at 2 min intervals for 10 min. Time to adequate anesthesia was also recorded. Results are presented as mean ± standard deviation. RESULTS: Rocuronium group demonstrated significantly better akinesia scores than control group at 2 min intervals post-PB (significant P value obtained). No significant complications were recorded. Rocuronium added to a mixture of LA improved the quality of akinesia in PB and reduced the need for supplementary injections. CONCLUSION: The addition of rocuronium 5 mg to a mixture of lidocaine 2% with adrenaline and hyaluronidase 50 IU/ml shortened the onset time of peribulbar anesthesia in patients undergoing cataract surgery without causing adverse effects. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5791268/ /pubmed/29416247 http://dx.doi.org/10.4103/joacp.JOACP_383_16 Text en Copyright: © 2018 Journal of Anaesthesiology Clinical Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Patil, Vishalakshi Farooqy, Allauddin Chaluvadi, Balaraju Thayappa Rajashekhar, Vinayak Malshetty, Ashwini Effect of the addition of rocuronium to 2% lignocaine in peribulbar block for cataract surgery |
title | Effect of the addition of rocuronium to 2% lignocaine in peribulbar block for cataract surgery |
title_full | Effect of the addition of rocuronium to 2% lignocaine in peribulbar block for cataract surgery |
title_fullStr | Effect of the addition of rocuronium to 2% lignocaine in peribulbar block for cataract surgery |
title_full_unstemmed | Effect of the addition of rocuronium to 2% lignocaine in peribulbar block for cataract surgery |
title_short | Effect of the addition of rocuronium to 2% lignocaine in peribulbar block for cataract surgery |
title_sort | effect of the addition of rocuronium to 2% lignocaine in peribulbar block for cataract surgery |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791268/ https://www.ncbi.nlm.nih.gov/pubmed/29416247 http://dx.doi.org/10.4103/joacp.JOACP_383_16 |
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