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Genetic engineering of Escherichia coli to improve L-phenylalanine production

BACKGROUND: L-phenylalanine (L-Phe) is an essential amino acid for mammals and applications expand into human health and nutritional products. In this study, a system level engineering was conducted to enhance L-Phe biosynthesis in Escherichia coli. RESULTS: We inactivated the PTS system and recruit...

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Detalles Bibliográficos
Autores principales: Liu, Yongfei, Xu, Yiran, Ding, Dongqin, Wen, Jianping, Zhu, Beiwei, Zhang, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791370/
https://www.ncbi.nlm.nih.gov/pubmed/29382315
http://dx.doi.org/10.1186/s12896-018-0418-1