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HER2 is not a cancer subtype but rather a pan-cancer event and is highly enriched in AR-driven breast tumors

BACKGROUND: Approximately one in five breast cancers are driven by amplification and overexpression of the human epidermal growth factor receptor 2 (HER2) receptor kinase, and HER2-enriched (HER2E) is one of four major transcriptional subtypes of breast cancer. We set out to understand the genomics...

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Detalles Bibliográficos
Autores principales: Daemen, Anneleen, Manning, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791377/
https://www.ncbi.nlm.nih.gov/pubmed/29382369
http://dx.doi.org/10.1186/s13058-018-0933-y