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CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis

Mechanisms of selective autophagy of the ER, known as ER-phagy, require molecular delineation, particularly in vivo. It is unclear how these events control ER proteostasis and cellular health. Here, we identify cell-cycle progression gene 1 (CCPG1), an ER-resident protein with no known physiological...

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Detalles Bibliográficos
Autores principales: Smith, Matthew D., Harley, Margaret E., Kemp, Alain J., Wills, Jimi, Lee, Martin, Arends, Mark, von Kriegsheim, Alex, Behrends, Christian, Wilkinson, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791736/
https://www.ncbi.nlm.nih.gov/pubmed/29290589
http://dx.doi.org/10.1016/j.devcel.2017.11.024