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CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis
Mechanisms of selective autophagy of the ER, known as ER-phagy, require molecular delineation, particularly in vivo. It is unclear how these events control ER proteostasis and cellular health. Here, we identify cell-cycle progression gene 1 (CCPG1), an ER-resident protein with no known physiological...
Autores principales: | Smith, Matthew D., Harley, Margaret E., Kemp, Alain J., Wills, Jimi, Lee, Martin, Arends, Mark, von Kriegsheim, Alex, Behrends, Christian, Wilkinson, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791736/ https://www.ncbi.nlm.nih.gov/pubmed/29290589 http://dx.doi.org/10.1016/j.devcel.2017.11.024 |
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