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New tricks for an old dog: Brf2-dependent RNA Polymerase III transcription in oxidative stress and cancer
Here, we discuss the role of Brf2, an RNA Polymerase III core transcription factor, as a master switch of the oxidative stress response. We highlight the interplay of Brf2 with the Nrf2/Keap1 pathway, as well as the role of Brf2 in cancer and other possible regulations.
Autores principales: | Gouge, Jerome, Vannini, Alessandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791813/ https://www.ncbi.nlm.nih.gov/pubmed/28854119 http://dx.doi.org/10.1080/21541264.2017.1335269 |
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